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Rhoden EL, Morgentaler A. Risks of testosterone-replacement remedy and suggestions for monitoring. Testosterone replacement in hypogonadal men with angina improves ischaemic threshold and high quality of life. Ajayi AAL, Mathur R, Halushka PV. Testosterone improve human platelet thromboxane A2 receptor density and aggregation responses.
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We report a case of an acute ST-segment elevation myocardial infarction in a affected person with conventional cardiac danger elements using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this patient additionally had polycythemia, probably secondary to high-dose testosterone. The patient underwent profitable percutaneous intervention of the right coronary artery. Physicians and patients should concentrate on the medical penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).
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Moreover, a part of endothelial dysfunction has been proposed, which may contribute to irregular vessel reactivity. However, testosterone in physiologic doses may even be helpful in sufferers with angina , have larger ischemic thresholds and improved quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and increases camsdoda coronary blood flow in males with established coronary artery illness . Therefore, an interaction of endogenous factors of the patient’s risk profile in addition to the testosterone dosing could also be problems with whether opposed events happen.
